Motor evoked potentials for multiple sclerosis: A multiyear follow-up dataset.

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  1. Hasselt University, Belgium


Published 09 Mar. 2021 | License CC-BY


Multiple sclerosis (MS) is a chronic disease affecting millions of people worldwide. The signal conduction through the central nervous system of MS patients deteriorates. Evoked potential measurements allow clinicians to monitor the degree of deterioration and are used for decision support. We share a dataset that contains motor evoked potential (MEP) measurements, in which the brain is stimulated and the resulting signal is measured in the hands and feet. This results in time series of 100 milliseconds long. Typically, both hands and feet are measured in one hospital visit. The dataset consists of 5586 visits of 963 patients, performed in day-to-day clinical care over a period of 6 years. The dataset consists of approximately 100,000 MEP. Clinical metadata such as the expanded disability status scale, sex, and age is also available. This dataset can be used to explore the role of evoked potentials in MS research and patient care. It may also be used as a real-world benchmark for machine learning techniques for time series analysis and predictive modelling.


| Multiple Sclerosis | Prognosis | Time series |


  • Yperman, J., Becker, T., Valkenborg, D., Popescu, V., Hellings, N., Wijmeersch, B. V., & Peeters, L. M. (2020). Machine learning analysis of motor evoked potential time series to predict disability progression in multiple sclerosis. BMC Neurology, 20(1).
  • Yperman, J., Becker, T., Valkenborg, D., Hellings, N., Cambron, M., Dive, D., Laureys, G., Popescu, V., Van Wijmeersch, B., & Peeters, L. M. (2020). Deciphering the Morphology of Motor Evoked Potentials. Frontiers in Neuroinformatics, 14.


  • The computational resources and services used in this work were provided by the VSC (Flemish Supercomputer Center) funded by the Research Foundation—Flanders (FWO) and the Flemish Government—department EWI.
  • Research Foundation—Flanders (FWO) for ELIXIR Belgium (I002819N) and Hermesfonds for ELIXIR Belgium, AH.2017.051, IO 17001306


Yperman J, Popescu V, Van Wijmeersch B, Becker T, Peeters L (2021) Motor evoked potentials for multiple sclerosis: A multiyear follow-up dataset.. G-Node.