Dataset

Longitudinal (8 wks) T2-weighted MRI and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke

Markus Aswendt¹, Olivia Käsgen¹, Frederique Wieters¹, Michael Diedenhofen², Dirk Wiedermann²

¹University Hospital Cologne
²Max Planck Institute for Metabolism Research

DOI: 10.12751/g-node.699mgv BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 50.9 GiB)

Published 09 Nov. 2020 | License CC BY-NC-SA

Description

Longitudinal MRI including T2-weighted (T2w) and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke lesions induced by photothrombosis (PT) monitored for 8 weeks (8 wks). The mice received either intranasal C3a (complement factor) or PBS treatment from day 7 to day 28 post stroke.

Keywords

References

Stokowska A, Aswendt M, Zucha D, Lohmann S, Wieters F, Moran Suarez J, Atkins AL, Li Y, Miteva M, Lewin J, Wiedermann D, Diedenhofen M, Torinsson Naluai Å, Abaffy P, Valihrach L, Kubista M, Hoehn M, Pekny M, Pekna M. Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity. J Clin Invest. 2023 Mar 30:e162253. Epub ahead of print. PMID: 36995772. https://doi.org/10.1172/JCI162253

Citation

Aswendt M, Käsgen O, Wieters F, Diedenhofen M, Wiedermann D (2020) Longitudinal (8 wks) T2-weighted MRI and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke. G-Node. https://doi.org/10.12751/g-node.699mgv