Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention
- 1Neural Computation Laboratory, Istituto Italiano di Tecnologia, Rovereto, Italy; Center for Mind and Brain Sciences (CIMeC), University of Trento, Rovereto, Italy; Center for Brain and Cognition, and Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain
- 2Biosciences Institute, Newcastle University, NE1 7RU, Newcastle upon Tyne, United Kingdom
- 3Neural Computation Laboratory, Istituto Italiano di Tecnologia, Rovereto, Italy
Published 29 Jan. 2021 | License Creative Commons Attribution-NonCommercial-ShareAlike-4.0 International
Achieving behavioral goals requires integration of sensory and cognitive information, across cortical laminae and cortical regions. How this computation is performed remains unknown. Using local field potential recordings and spectrally resolved conditional Granger causality (cGC) analysis, we mapped visual information flow, and its attentional modulation, between cortical layers within and between macaque areas V1 and V4. Stimulus induced inter-laminar information flow within V1 dominated upwardly, channeling information towards supragranular cortico-cortical output layers. Within V4, information flow dominated from granular to supragranular layers, but interactions between supragranular and infragranular layers dominated downwardly. Low-frequency across-area communication was stronger from V4 to V1, with little layer specificity. Gamma-band communication was stronger in the feedforward V1 to V4 direction. Attention to the receptive field of V1 decreased communication between all V1 layers, except for granular to supragranular layers interactions. Communication within V4, and from V1 to V4, increased with attention across all frequencies. While communication from V4 to V1 was stronger in lower frequency bands (4-25 Hz), attention modulated cGCs from V4 to V1 across all investigated frequencies. Our data show that top down cognitive processes result in reduced communication within cortical areas, increased feedforward communication across all frequency bands and increased gamma band feedback communication.
Keywords| Neuroscience | Visual Attention | Laminar circuitry |
- Ferro, D., van Kempen, J., Boyd, M., Panzeri, S. and Thiele, A., 2020. Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention. bioRxiv.Ferro, D., van Kempen, J., Boyd, M., Panzeri, S. and Thiele, A., 2020. Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention. bioRxiv. https://doi.org/10.1101/2020.06.09.142190
- Funded by the Wellcome Trust  (JvK MB, AT), MRC [MR/P013031/1] (JvK, AT), NIH Brain Initiative [R01 NS108410] and [U19 NS107464U19] (SP) and Simons Foundation SFARI Explorer grant  (SP).