Dataset
Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types
- 1Institute for Ophthalmic Research, University of Tübingen, Germany
- 2Stanford Bio-X and Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, US
DOI: 10.12751/g-node.89z5px BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 172 MiB)
Published 03 Feb. 2025 | License Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License
Description
This repository contains the data and analysis pipeline underlying the analyses published in Dyszkant et al. (2025). Using the rd10 mouse model, which mirrors the human condition, our study examined its disease progression. Here, we addressed if and how the response diversity of functional RGC types changes with rd10 disease progression.
Keywords
| neuroscience | retinal ganglion cells | retinal degeneration | rd10 |References
- Nadine Dyszkant, Jonathan Oesterle, Yongrong Qiu, Merle Harrer, Timm Schubert, Dominic Gonschorek*, and Thomas Euler* (2024). Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types. bioRxiv. https://doi.org/10.1101/2024.09.06.610955
- Tom Baden, Philipp Berens, Katrin Franke, Miroslav Román Rosón, Matthias Bethge & Thomas Euler (2016). The functional diversity of retinal ganglion cells in the mouse. Nature 529, 345–350. https://doi.org/10.1038/nature16468
Funding
- Open Access Publishing Fund of the University of Tübingen
- Tistou & Charlotte Kerstan Stiftung RI-FG P3 EU/SCH 1-2& 3 Dysz
- DFG SFB 1233 "Robust Vision", 276693517; EU 42/10-1; EU 42/12-1