Dataset

Interactive effects of dopamine transporter genotype and aging on resting-state functional networks

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  1. 1Chair of Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, Dresden 01069, Germany
  2. 2Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan
  3. 3Clinical Neurophysiology and Memory Group, Institute of Cognitive Neuroscience, University College London, WC1N3AR London
  4. 4Department of Biomedical Engineering, School of Life and Health Sciences, Aston University, Birmingham, B47ET, UK

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Published 24 Mar. 2019 | License Creative Commons CC0 1.0 Public Domain Dedication


Description

The resting-state fMRI data are fully preprocessed and arranged in 4D nifti files. Preprocessing was carried out using SPM 12 (slice-time correction, spatial unwarping, normalizing to MNI space, smoothing with an 8 mm Gaussian kernel) and FSL's ICA-AROMA (additional head-motion correction). Furthermore, the resting-state fMRI data were bandpass filtered (band: 0.009 - 0.08 Hz) and mean WM and CSF signals were regressed out. Behavioral data contain information on age, sex and the individual scores on the Raven's matrices test, the Stroop test (variables: accuracy on incongruent color and reaction time of incongruent color), the spot-a-word test and the identical pictures test.

Keywords

| Resting-state fMRI | Aging | Dopamine transporter gene | DAT1 | Graph theory | Functional connectivity | Cognitive testing | Participation coefficient | Brain-behavior correlations |

References

  • Baeuchl C, Chen H-Y, Su Y-S, Hämmerer D, Klados MA, Li S-C (2019) Interactive effects of dopamine transporter genotype and aging on resting-state functional networks. PLoS ONE 14(5):e0215849

Funding

  • DFG LI 879/12-2
  • DFG SFB 940/2, Project B3

Citation

Baeuchl C, Chen H, Su Y, Hämmerer D, Klados MA, Li S (2019) Interactive effects of dopamine transporter genotype and aging on resting-state functional networks. G-Node. https://doi.org/10.12751/g-node.f13e77