A robust receptive field code for optic flow detection and decomposition during self-motion
- University of Tübingen, Werner Reichardt Centre for Integrative Neuroscience and Institute of Neurobiology, 72076 Tübingen, Germany
DOI: 10.12751/g-node.hkzu3l BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 1.9 GiB)
Published 08 Mar. 2022 | License Creative Commons CC BY-NC-SA 4.0 International (Attribution-NonCommercial-ShareAlike)
The perception of optic flow is essential for any visually guided behaviour of a moving animal. To mechanistically predict behaviour and understand the emergence of self-motion perception in vertebrate brains, it is essential to systematically characterize the motion receptive fields (RFs) of optic flow processing neurons. Here, we present the fine-scale RFs of thousands of motion-sensitive neurons studied in the diencephalon and the midbrain of zebrafish. We found neurons that serve as linear filters and robustly encode directional and speed information of translation-induced optic flow. These neurons are topographically arranged in pretectum according to translation direction. The unambiguous encoding of translation enables the decomposition of translational and rotational self-motion information from mixed optic flow. In behavioural experiments, we successfully demonstrated the predicted decomposition in the optokinetic and optomotor responses. Together, our study reveals the algorithm and the neural implementation for self-motion estimation in a vertebrate visual system.
Keywords| Neuroscience | Zebrafish | Receptive field | Visual motion integration | Optic flow decomposition | Matched filter algorithm | Optomotor responses | Optokinetic responses | visually guided behaviour | Diencephalon |
- Zhang, Y., Huang, R., Nörenberg, W., & Arrenberg, A. (2021). A robust receptive field code for optic flow detection and decomposition during self-motion. bioRxiv. https://doi.org/10.1101/2021.10.06.463330
- Zhang, Y., Huang, R., Nörenberg, W., & Arrenberg, A. A robust receptive field code for optic flow detection and decomposition during self-motion (in review).
- Deutsche Forschungsgemeinschaft (DFG) grant EXC307 (CIN – Werner Reichardt Centre for Integrative Neuroscience)
- Deutsche Forschungsgemeinschaft (DFG) grant INST 37/967-1 FUGG
- Human Frontier Science Program (HFSP) Young Investigator Grant RGY0079