Dataset
Nighttime-specific gene expression changes in suprachiasmatic nucleus and habenula are associated with resiliency to chronic social stress
- 1Center for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi, UAE
- 2Department of Biology, New York University Abu Dhabi, Abu Dhabi, UAE
- 3Core Technology Platforms, New York University Abu Dhabi, Abu Dhabi, UAE
- 4NYUAD Research Institute, New York University Abu Dhabi, Abu Dhabi, UAE
DOI: 10.12751/g-node.jj57l9 BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 160 GiB)
Published 06 Sep. 2024 | License Creative Commons Attribution 4.0 International Public License
Description
We provide bulk RNA transcriptome of suprachiasmatic nucleus and habenula at four distinct timepoints within a 24-hour cycle following exposure to chronic social defeat stress. The four timepoints are: ZT4 (1100 hrs), ZT10 (1700 hrs), ZT16 (2300 hrs), ZT22 (0500 hrs). The three sampled phenotypes are stress-resilient, stress-susceptible and stress-naive mice. Supporting behavioural data (social interaction and locmotion) is also available.
Keywords
| Neuroscience | Chronic Stress | Circadian Rhythms | Suprachiasmatic Nucleus | Habenula | Mood | RNA |References
- Narain, P., Petković, A., Šušić, M., Haniffa, S., Anwar, M., Arnoux, M., Drou, N., Antonio-Saldi, G., Chaudhury., D. (2024) Nighttime-specific differential gene expression in suprachiasmatic nucleus and habenula is associated with resilience to chronic social stress. Translational Psychiatry 14(1), 407. https://doi.org/10.1038/s41398-024-03100-w