Dataset
Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice
- 1Research Group Synaptic Wiring and Information Processing, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany
- 2Institute of Developmental Neurophysiology, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany
DOI: 10.12751/g-node.lkx6kk BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 123 GiB)
Published 25 Jan. 2022 | License Creative Commons CC0 1.0 Public Domain Dedication
Description
Large-scale, annotated collection of 2-photon calcium imaging data and electrophysiological recordings in CA1 of the murine hippocampus under three distinct anesthetics (Isoflurane, Keta/Xyl and MMF), during natural sleep, and during wakefulness.
Keywords
| Neuroscience | Anesthesia | Anaesthesia | Sleep | Recovery | Hippocampus | CA1 | Pyramidal neurons | Calcium imaging data | Electrophysiological recordings | Pupillometry | EMG data |References
- Formozov, A. et al. Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice. Scientific data. 2022
- Yang, W., Chini, M. et al. Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation. PLoS biology, 19(4), e3001146 https://doi.org/10.1371/journal.pbio.3001146
- Formozov A, Chini M, Dieter A, Yang W, Pöpplau JA, Hanganu-Opatz IL, Wiegert JS (2022) Calcium imaging of hippocampal activity under anesthesia and natural sleep in mice. G-Node. https://doi.org/10.12751/g-node.s549qk
Funding
- German Research Council SFB936/B8
- German Research Council SFB936/B5
- European Research Council ERC-2016-StG-714762
- European Research Council ERC-2015-CoG-681577
- Alexander von Humboldt Foundation Research Fellowship
- EU-project euSNN MSCA-ITN-H2020-860563
- Landesforschungsförderung Hamburg LFF76 and LFF73
- Chinese Scholarship Council CSC 201606210129