Dataset
Association of verbal and non-verbal theory of mind abilities with non-coding variants of OXTR in youth with autism spectrum disorder and typically developing individuals: a case control study
- 1Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran
- 2School of Cognitive Sciences, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran
- 3Department of Cellular and Molecular Science, Roshd Azma Company, Alborz, Iran
- 4Research Center for Cognitive and Behavioral Sciences, Roozbeh Psychiatry Hospital, Tehran University of Medical Sciences, Tehran, Iran
DOI: 10.12751/g-node.mk9n4h BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 20 KiB)
Published 06 Jun. 2023 | License Creative Commons CC0 1.0 Universal
Description
In the present study, we examined the association between rs2268498 and rs53576 and social functioning in individuals with ASD and TD group. We found preliminary evidence that rs2268498 and rs53576 are associated with ToM related abilities in healthy individuals as well as in autistic individuals. Accordingly, rs2268498 may play an important role in predicting ToM capabilities. It will be necessary to conduct further research to address the association of genetic variants with a deficit in ToM in individuals with ASD.
Keywords
| autism spectrum disorder | Theory of Mind | oxytocin receptor gene | rs2268498 | rs53576 |References
- Rana Ghamari, Mohammad Tahmaseb, Atiye Sarabi-Jamab, Seyed-Alireza Etesami, Azar Mohammadzadeh, Fatemeh Alizadeh, Mehdi Tehrani-Doost: Association of verbal and non-verbal theory of mind abilities with non-coding variants of OXTR in youth with autism spectrum disorder and typically developing individuals: a case control study. BMC Psychiatry Journal, submitted.