Dataset
Autism risk gene Cul3 alters neuronal morphology via Caspase-3 activity in mouse hippocampal neurons
- University of Alabama at Birmingham
DOI: 10.12751/g-node.qdqcp3 BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 136 MiB)
Published 22 Apr. 2024 | License Creative Commons CC0 1.0 Public Domain Dedication
Description
Cul3 regulates the formation or maintenance of cell morphology, GABAergic synaptic puncta, and neuronal viability in developing hippocampal neurons in culture.
Keywords
| cullin-3 | dendrite | axon | spine | synapse | caspase-3 |References
- Xia Q-q, Singh A, Wang J, Xuan ZX, Singer JD and Powell CM (2024) Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons. Front. Cell. Neurosci. 18:1320784. https://doi.org/10.3389/fncel.2024.1320784
Funding
- National Institute of Mental Health (NIMH) R01 MH113948
- Civitan International Research Center Emerging Scholar Award