Dataset

Task-specific modulation of corticospinal neuron activity during motor learning

Najet Serradj¹, Francesca Marino², Yunuen Moreno-López¹, Amanda Bernstein¹, Sydney Agger³, Marwa Soliman¹, Andrew Sloan⁴, Edmund Hollis¹

¹Burke Neurological Institute
²University of California, San Francisco
³HAVAS Production Studios
⁴Vulintus, Inc., Lafayette, Colorado, USA

DOI: 10.12751/g-node.sbrmy3 BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 631 MiB)

Published 14 Apr. 2023 | License Creative Commons CC0 1.0 Public Domain Dedication

Description

The learning of motor skills relies on plasticity of the primary motor cortex as task acquisition drives the remodeling of cortical motor networks. Large scale cortical remodeling of evoked motor outputs occurs in response to the learning of precise, corticospinal-dependent behavior, but not simple, imprecise tasks. Here we determine the response of corticospinal neurons to both precise and imprecise motor training and assess the role of corticospinal neuron activity in the execution of the trained behaviors.

Keywords

| Neuroscience | Calcium Imaging | Motor Learning |

References

Serradj N, Marino F, et al. (2022) Refinement of corticospinal neuron activity during skilled motor learning. bioRxiv. https://doi.org/10.1101/2021.03.22.436415

Funding

National Institutes of Health DP2 NS106663
National Institutes of Health R03 NS103070

Citation

Serradj N, Marino F, Moreno-López Y, Bernstein A, Agger S, Soliman M, Sloan A, Hollis E (2023) Task-specific modulation of corticospinal neuron activity during motor learning. G-Node. https://doi.org/10.12751/g-node.sbrmy3