Dataset

Resolution of subcomponents of EPSCs in rat hair-cell/auditory-nerve fiber synapses

Eric Young¹, Jingjing Wu², Mamiko Niwa¹, Elisabeth Glowatzki¹

¹Johns Hopkins Univ.
²Harvard Medical School

DOI: 10.12751/g-node.ylt20r BROWSE REPOSITORY BROWSE ARCHIVE DOWNLOAD ARCHIVE (ZIP 84 MiB)

Published 22 Jun. 2020 | License Creative Commons CC0 1.0 Public Domain Dedication

Description

The synapse between inner hair cells and auditory nerve fiber dendrites in rats shows large EPSCs, which are either monophasic or multiphasic. EPSCs were deconvolved to allow analysis of individual releases of neurotransmitter. The results were used to analyze and test models of synaptic release in the hair cell.

Keywords

References

Wu JS, Young ED, and Glowatzki E. 2016. Maturation of spontaneous firing properties after hearing onset in rat auditory nerve fibers: Spontaneous rates, refractoriness, and interfiber correlations. J. Neurosci. 36:10584-10597. https://doi.org/10.1523/JNEUROSCI.1187-16.2016
Young, E.D., Wu, J.J., Niwa, M., and Glowatzki, E. 2020. Resolution of subcomponents of synaptic release from post-synaptic currents in rat hair-cell/ auditory-nerve fiber synapses. BioRχiv 2020.05.13.070920. https://doi.org/10.1101/2020.05.13.070920

Funding

NIDCD R01DC006476
NIDCD R01DC012957
NIDCD P30DC005211

Citation

Young E, Wu J, Niwa M, Glowatzki E (2020) Resolution of subcomponents of EPSCs in rat hair-cell/auditory-nerve fiber synapses. G-Node. https://doi.org/10.12751/g-node.ylt20r